Optimized Synthesis of Xanthan gum/ZnO/TiO2Nanocomposite with High Antifungal Activity against Pathogenic Candida albicans

Increased resistance of fungal pathogens to common antimicrobial agents is known as one the most important human problems. Due limited variety antifungal drugs available, identification and use new are essential. This study aimed determine optimal conditions for synthesizing a novel nanocomposite xanthan gum/ZnO/TiO2with highest activity against Candida albicans (C. albicans). For this purpose, nine experiments were designed using Taguchi method. In experiments, three factors gum, ZnO, TiO2nanoparticles have been investigated at different levels, best ratio with was determined. The results showed that in presence synthesized experiment 3 (xanthan gum 0.01 M, ZnO 0.09 TiO2 M), inhibition growth reached 92.51%. properties its components characterization methods, which confirmed formation nanocomposites desirable properties. an agent has effective performance can be used well various fields.